By (auth.), Frederick L. Greene M.D., David L. Page M.D., Irvin D. Fleming M.D., April G. Fritz C.T.R., R.H.I.T., Charles M. Balch M.D., Daniel G. Haller M.D., Monica Morrow M.D. (eds.)
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The doser to the midline the primary, the ~reater the risk of bilateral cervical nodal spread. Any prevlOUS treatment to the neck, surgical and/or radiation, may alter normal lymphatic drainage patterns, resulting in unusual distribution of regional spread of disease to the cervicallymph nodes. In general, cervicallymph node involvement from oral cavity primary sites is predictable and orderly, spreading from the primary to upper, then middle, and subsequently lower cervical nodes. However, disease in the anterior oral cavity mayaIso spread directly to the midcervicallyrnph nodes.
5A. Five-year, observed survival by "combined" AJCC stage for squamous cell carcinoma ofthe hypopharynx, 1985-1991. 0 CASES 304 350 620 1688 FIG. 58. Five-year, relative survival by "combined" AJCC stage for squamous cell carcinoma ofthe hypopharynx, 1985-1991. ) 40 American Joint Committee on Cancer' 2002 BIBLIOGRAPHY Boyd TS, Harari PM, Tannehill SP, Voytovich MC, Hartig GK, Ford CN, Foote RL, Campbel! BH, Schultz CJ: Planned postradiotherapy neck disseetion in patients with advanced head and neck cancer.
Anatomie sites and histologie types were coded on the NCDB according to the second edition of the International Classification ofDiseases for Oncology (ICD0-2). The subsites to be included in each analysis were chosen on the basis of those listed in the fourth edition of the AJCC's Manual for Staging of Cancer. Survival analyses for the lip, oral cavity, oropharynx, nasopharynx, hypopharynx, and the larynx's subsites included squamous ce11 carcinomas only (M8050, 80518082). Survival analyses for the maxillary sinus and major salivary glands included a11 histologie types.
AJCC Cancer Staging Manual by (auth.), Frederick L. Greene M.D., David L. Page M.D., Irvin D. Fleming M.D., April G. Fritz C.T.R., R.H.I.T., Charles M. Balch M.D., Daniel G. Haller M.D., Monica Morrow M.D. (eds.)
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